SiO2 Silicon Dioxide Powder Pharmaceutical Coatings Food Grade CAS
Quartz (SiO2); Rose quartz; silica,crystalline(asrespirable;
silica,crystalline(asrespirabledust); Silicon oxide, quartz;
CRYSTALLINE SODIUM POTASSIUM ALUMINOSILICATE; HYDRANAL(R)-MOLECULAR
SIEVE;ALUMINUM SODIUM SILICATE ;
within 24 hours upon receipt of payment
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Silicon Dioxide is widely used in pharmaceutical formulations,
cosmetics, and food products. It is also widely used in
orally-dosed nutritional products and regarded as an essentially
nontoxic, nonirritant excipient. Silicon dioxide readily absorbs
large quantities of water from its surroundings, and does this
without itself liquefying.Silica is a common additive in the
production of foods, where it is used primarily as a flow agent in
powdered foods, or to adsorb water in hygroscopic applications. It
is the primary component of diatomaceous earth. Colloidal silica is
also used as a wine, beer, and juice fining agent.
In the pharmaceutical industry, silicon dioxide has many uses in
tablet-making: some include as an anti-caking agent, adsorbent,
disintegrant, or glidant to allow powder to flow freely when
tablets are processed.
The major application of silica in solid-dosage forms is as a
glidant and anti-static agent to improve the flow properties of
granulations in high-speed tablet and capsule machines. Particulate
flow has a direct effect on weight uniformity and plays an
important role in solid-solid blending and powder homogeneity.
Glidants reduce friction between particles and function to improve
the flow of granulations in the manufacturing process. Silica also
fills surface irregularities in granules, reducing
inter-particulate friction and improving flow. Glidants also
prevent the segregation and separation of granules caused by
excessive vibration in a tablet press or capsule press. The
presence of silica in a tablet granulation prevents cavitation or
surging of the powder blend that often occurs in direct compression
formulations. Uniformity in tablet hardness and tablet weight
results from formulations flowing evenly into the die cavity during
tabletting operations. Silica is generally used as a glidant at a
concentration range of 0.1%-0.75%, and is typically used at the
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